Nonito forces fighters out of the division

Pharmacokinetic studies verified the presence ofthe engineered shRNA in the intestinal mucosa, proving successful delivery ofthe active hairpin RNA component by the bacterial system. Cequent developedthe current tkRNAi candidate on the basis of an E. coli delivery platformobtained from the laboratory of Patrice Courvalin at the Institut Pasteur.Cequent is planning to start a Phase I clinical trial for the indication ofFAP in 2009.About Cequent Pharmaceuticals, Inc. Cequent'sfirst products, now in pre-clinical development, are drug candidates targetingcolon-cancer prevention and inflammatory bowel disease.

The company designedits powerful tkRNAi technology to deactivate specific disease-causing genessafely and effectively, using non-pathogenic bacteria as an engine to produceand deliver RNAi directly into cells. It is based on ground-breakingscientific research originating at the Institut Pasteur (Paris, France) and atthe Beth Israel Deaconess Medical Center/Harvard Medical School. A privatelyheld company based in Cambridge, Massachusetts, Cequent was established in2006.SOURCECequent PharmaceuticalsCaroline Grossman for Cequent Pharmaceuticals, 1-781-771-5579,. Paul Williams has been coined “The Most Avoided Fighter” and for good reason. He’s had to fight in multiple divisions since none of the top fighters in the welterweight division were willing to fight him.Still, he’s been able to step into the ring with respectable and recognizable fighters such as Carlos Quintana, Antonio Margarito, and Vernon Philips.Nonito’s list of recent victims on the other hand includes the following names: Luis Maldonado, Raul Martinez, and Rafael Concepcion.

They are solid and respectable fighters, but none of them were considered elite fighters.Nonito Donaire seemed to be destined for stardom after destroying Darchinyan, considering the rising numbers boxing fans within the Filipino community.Unfortunately, he’s been avoided like the plague consistently by the top fighters in his division.Darchinyan’s team never seriously tried to get a rematch with Donaire, and instead the "Raging Bull" moved up to the Super Flyweight Division.He’s called out fighters such Daisuke Naito and Takefumi Sakata, but neither showed any inkling on sharing the ring with Donaire. Forget the excuses about Japan’s unwillingness to recognize IBF, WBO, and IBO as legitimate world titles. Fernando Montiel a few months ago, but it fell apart when Fernando decided to move up to bantamweight for the reason that he can no longer make the weight for the super flyweight division.Fernando is a great fighter and I don’t think he’s avoided Donaire, but it seems that whenever a fight with Nonito is within reach; his opponents suddenly have the inkling to move out of the division or find other excuses to not fight Donaire.Paul Williams was forced to fight in multiple divisions to get notable fights.Nonito forces fighters out of the division.Nonito has moved up to the Super Flyweight division, but still has not found success in luring any of the top fighters to meet him in the ring.Darchinyan has been vocal recently about facing Donaire again. But that’s because he needs Donaire again to gain credibility, as he was exposed by Agbeko.