Carter made his official visit to Missouri on Dec

For the second weekend in succession, the Missouri Tigers have made an indelible impression on the national recruiting trail.According to Missouri's Rivals affiliate, Power Mizzou, the Tigers secured verbal commitments from three players over the weekend, including coveted receivers Bud Sasser (Denton, TX) and Marcus Lucas (Liberty, MO).Sasser and Lucas each reportedly confirmed the decision to Power Mizzou via text message on Saturday.Daniel Easterly, a 6'4" 178-pound three-star safety from the Detroit area, confirmed his commitment to the site on Friday evening.Easterly was committed to Illinois, to whom he pledged verbally in June, but a mid-November visit to Columbia brought Missouri into the picture. Amid rumors he was planning to decommit from the Illini in favor of the Tigers, Easterly paid a visit to Champaign a week ago and didn't arrive at his ultimate decision until recently."It was just in the last couple days, like the past week," Easterly told Power Mizzou on Friday. "I've been talking to my brothers and my close family about it, and this is for the best."And the list of commitments for MU's 2010 class may be growing.Though it has yet to be confirmed by either player, defensive end Matt Hoch and defensive back Dexter McDonald each appear close to switching their verbal pledges to Missouri. The 6'5", 230-pound Hoch, who is the younger brother of MU offensive tackle Dan Hoch, is presently listed by Rivals as a "solid verbal" pledge to the Iowa Hawkeyes.According to the recruiting site, McDonald, a 6'2", 180-pound cornerback from Kansas City, is currently committed to Illinois, to whom he pledged back in June.Like Sasser and Lucas, both Hoch and McDonald were in Columbia this weekend for an official visit.Rated by Rivals as the No. Prior to his commitment, Sasser had taken visits to Arizona and Nebraska and was also considering Kansas.Provided the hype surrounding each player plays out, Sasser and Lucas highlight the class' trio of heralded receivers, which also includes four-star prospect Jimmy Hunt from Cahokia, Ill.Widely regarded as one of the top two players in the state of Missouri, the 6'5", 195-pound Lucas was sought after by programs all over the nation.Holding offers from at least 11 programs, Lucas paid visits to Oklahoma, Arkansas, and even Stanford, whose academic reputation had an enticing effect on the 3.7 GPA student.As his recruitment progressed, it seemed almost a certainty that Lucas would save his decision for after the holidays, validating speculation that he was preparing to announce his suitor on national television after the Jan. 9 U.S Army All-American Bowl, a game in which he was invited to participate.Evaluated as the 14th-best receiver in the nation, with his pledge to Missouri this weekend, Lucas is seemingly the cherry on top of a class that may end up the best ever in MU history.Now with seven four-star commits among its 22 members, according to Rivals' ratings released Sunday, Missouri's 2010 class is ranked No 14 in the country That's up four slots from this time last week. Just two weeks ago, prior to MU's pair of recent weekend recruiting bonanzas, the Tigers weren't even ranked in the top 40.(On a side note, to illustrate the discrepancies between these recruiting sites, Scout currently has MU's class ranked No.

28 with only three four-star prospects.)Perhaps even more significant is that this class represents MU's improving ability to retain high-profile recruits from within the state.Of the players considered by Rivals to be Missouri's 10 best, five are committed to Missouri, including offensive lineman Nick Demien (Wentzville), Lucas, and defensive end Kony Ealy (New Madrid), who comprise the top three, respectively.Not since 2004, when running back Tony Temple, quarterback Chase Patton, and offensive lineman Kyle Riggs each committed to the Tigers, has Missouri landed each of the state's top three players.Now, with the number of available scholarships presumably dwindling, it remains to be seen whether the Tigers will attempt to romance any more recruits. Toss Hoch and McDonald into the mix, and MU's class may be very close to reaching maximum capacity.Keeston Terry, a receiver from Blue Springs, MO, who is rated as the state's No. 4 player, was among the visitors in Columbia this weekend, but the verbal pledge he gave to Kansas in August may appear too strong to break.The one piece of low-hanging fruit that may remain for Missouri, depending on the remaining space available in the class, is Stonewall, Lou., athlete/wide receiver Curtis Carter .Carter made his official visit to Missouri on Dec. 11-12 after decommiting from Nebraska days prior, but he chose not to follow the lead of fellow one-time Cornhusker commit Tyler Gabbert, Texas running back Marcus Murphy, and JUCO transfer Kenronte Walkerall of whom committed to MU during their visits with the Tigers last weekend.Carter, who as of Sunday has MU and TCU listed as his top two choices, visited the Horned Frogs this weekend. LOS ANGELES(Business Wire)KYTHERA Biopharmaceuticals, Inc.

(KYTHERA) today announced that it hassuccessfully completed two Phase 2 clinical studies demonstrating the efficacy,safety, and tolerability of its lead product candidate, ATX-101, for thereduction of submental (under-the-chin) fat. The two Phase 2, randomized,double-blind, placebo-controlled, dose-ranging studies enrolled a total of 157patients and were conducted across 10 centers in the United Kingdom, Canada, andAustralia Multiple physician and patient endpoints were evaluated. In both studies, ATX-101 was safe and tolerable and demonstrated statisticallysignificant efficacy versus placebo. The demonstrated aesthetic correction wasclinically meaningful and was matched by improvements in patient reportedoutcomes. "We are very pleased with the results and the aesthetic correction patientsachieved. ATX-101 has the potential to be the first drug approved for thereduction of localized facial fat and an important tool for physicians inachieving optimal aesthetic outcomes for their patients," said Patricia Walker,MD, PhD, KYTHERAs Chief Medical Officer. "We look forward to presentingexpanded results from these studies in a future peer-reviewed forum." Study DesignsStudy 0603 was a Phase 2, randomized, double-blind, placebo-controlled,dose-ranging study which enrolled 85 patients at five centers in the UnitedKingdom, Canada, and Australia.

This study varied drug concentrations whilefixing other dosing parameters. Study 0707 varied injection spacing and volume at a fixed drugconcentration The study endpoints were identical to Study 0603. About ATX-101ATX-101 is a first-in-class injectable product being studied for the reductionof small volumes of fat. ATX-101 clinical research is focused on treatinglocalized facial fat deposits, including submental fat. KYTHERA has completedtwo international randomized, double-blind, placebo-controlled, Phase 2 studieswith ATX-101 in the treatment of submental fat as well as a U.S Phase 1pharmacokinetic study.